Trial establishes new standard of care for chronic hepatitis C infection

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Protease inhibitors for the treatment of chronic hepatitis C genotype-1 infection: the new standard of care.

For the past decade, the standard treatment for chronic hepatitis C infection has been pegylated-interferon plus ribavirin. With US Food and Drug Administration approval of boceprevir and telaprevir--two protease inhibitors--the standard-of-care treatment for genotype-1 infection, the main genotype worldwide, is now peginterferon plus ribavirin and a protease inhibitor. Rates of sustained virol...

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[New paradigm for treatment of chronic hepatitis C virus infection].

교신저자: 정우진, 700-712, 대구시 중구 달성로 56, 계명대학교 의과대학 내과학교실 Correspondence to: Woo Jin Chung, Department of Internal Medicine, School of Medicine Keimyung University, 56 Dalsung-ro, Jung-gu, Daegu 700-712, Korea. Tel: +82-53-250-7088, Fax: +82-53-250-7442, E-mail: [email protected] Financial support: None. Conflict of interest: None. 요약: 페그인터페론의 등장 이후로 만성 C형간염의 치료 성적은 유의하게 개선되어 왔지만 치료시 동반되는 부작용과 일부 유전...

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A New Evolutionary Model for Hepatitis C Virus Chronic Infection

Hepatitis C virus (HCV) infects an estimated 3% of humanity [1] and is a leading global cause of liver disease and liver cancer [2]. Intervention is currently limited by the lack of a vaccine and of universally successful drug treatments. Although several next-generation drugs (e.g., direct-acting protease-inhibitors) are already improving outcomes, a number of factors will affect overall treat...

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Chronic hepatitis C virus infection.

CHRONIC HEPATITIS C VIRUS (HCV) infection is a common worldwide problem. The infection may progress to cirrhosis with the subsequent development of complications such as ascites, encephalopathy, variceal bleeding, and hepatocellular carcinoma. Thus, early detection and therapy is of great importance. There has been substantial progress in understanding various aspects of HCV infection, includin...

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Chronic hepatitis C virus infection, a new cardiovascular risk factor?

Among the large scope of extrahepatic manifestations related to hepatitis C virus (HCV) infection, many studies recently evaluated the frequency and characteristics of cardiovascular involvement. To assess the current published data on HCV infection and cardiovascular diseases. Published studies on cardiovascular disease, i.e. cerebrovascular accident and ischaemic heart disease in subjects wit...

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ژورنال

عنوان ژورنال: Weekly releases (1997–2007)

سال: 1998

ISSN: 9999-1233

DOI: 10.2807/esw.02.46.01124-en